How to Boost Your Immune System

Evidence Based Research On How To Boost Your Immune System

There are many great supplements and foods to help support your immune system. We are certainly in interesting times now and with varying symptoms associated with this pandemic virus, it would be important to consider a variety of care. Why can this virus have so many symptoms you might be wondering? It’s all due to angiotensin-converting enzyme 2 or ACE2 receptor. This protein provides an entry point for the virus to infect cells, like a key to a lock. ACE2 receptors are found in many tissues including the lungs, heart, blood vessels, kidneys, liver and gastrointestinal tract and due to this, the body can suffer in many ways.

What is ACE2?

ACE2 helps modulate many activities of a protein called angiotensin 2 (ANG 2) that increases blood pressure and inflammation. This can damage blood vessel linings and cause various tissue injuries. When the virus binds to the receptor sites, it prevents the conversion of ANG2 to other molecules that are protective. ACE2 on our cells can vary in quantity from person to person with some evidence suggesting that they might be higher in people with diabetes, hypertension and coronary heart disease.  With less ACE2 available due to viral occupation, it could potentially contribute to more ANG 2 mediated injury.

What can you do to help yourself?

To help strengthen the immune system, it could be beneficial to combine a broad range of supplementation/foods including anti-inflammatory, anti-coagulant, anti-microbial and antioxidants. 70% – 80% of your immunity is derived from the gut so consider improving your immune system by providing your body with the powerful tool of good nutrition to give it a good fight to stay and feel well. It has been reported that the more the body is inflamed (co-morbidities), the sicker it can get with this virus, and it seems that sugar seems to be one of our greatest issues in our society. A recent publication in a technology paper states that data mining has searched through 400,000 scholarly articles on the pandemic finding the increase in risk of respiratory infections in those with high glucose levels. In this population study, both high and low pre-infection levels were associated with increased risk of COVID infection.  To “starve a fever” is something we’ve heard of before. We could benefit here in reducing sugars (carbohydrates) including alcohol ( often full of sugar) by intermittent fasting or considering a higher protein diet, the caveat however is not to eat an excessive amount of red meat and dairy.

Balancing the omega pathways are important as some are inflammatory, and some are anti-inflammatory. One area of significant importance is an excess involving Omega 6. This pathway of Arachidonic Acid, found in high quantities in red meat, dairy, shellfish, and squid mediates an enzyme called COX2 that causes an increase in Prostaglandins 2 (inflammatory) leading to an increase in thromboxane. Thromboxane causes blood clotting and constriction of blood vessels.  Red meat and a lot of dairy can therefore drive thromboxane and sugar drives another enzyme called delta-5-desturase that increases prostaglandin 2 as well and therefore thromboxane.

Here is a list of immune boosting ingredients you can incorporate into your diet to help maintain or improve health.

Vitamin C

Taking vitamin C for a cold is probably not a new concept to you. It’s a personal bodyguard, protecting cells and assisting healing. As it is required for your adrenal glands, the more stressed you are, the more your body chews it up which is potentially why someone with significant stress will tend to become unwell a little easier. It works hard in the liver, protecting DNA. It also helps your body make collagen, to keep you looking younger. It exerts effects in both the innate and adaptive immune system. A potent antioxidant, its action as a cofactor in numerous enzyme functions plays a key role in immune modulating effects including microbial killing, neutrophil migration and oxidant generation.

A good squeeze of lemon juice in lukewarm water first thing in the morning, not only gives you a dose of Vitamin C, but also helps alkalinize the body.

Ginger

Ginger is an effective antibacterial and antiviral. It is also a helpful antiparasitic and antifungal. In other words, it is great at helping get rid of quite a few nasties that can create havoc in the body. There even has been some evidence for helping heal stomach ulcers. The good news with ginger is that it inhibits the prostaglandins 2 conversion to thromboxane. Turmeric, fish oils and aspirin as you probably know well are beneficial here too.

Turmeric

The incredibly safe turmeric has over 10,000 peer reviewed articles of its benefits, it is therefore no wonder that it is the most frequently mentioned medicinal herb in science. One of the types of chemical compounds found in turmeric are curcuminoids. It is considered one of the most effective anti-inflammatories in the world. As inflammation is the cause of most diseases, reducing inflammation in the body is of paramount importance. Studies have also found turmeric useful for depression, blood clot prevention, cancer treatment, pain, Type2 diabetes and multiple skin conditions. For skin conditions, it could help speed up wound healing, calm the pores and decrease acne and acne scarring. Turmeric also binds to cadmium and lead and can be therefore useful in body detoxification.

Zinc and Quercetin

Zinc is highly important for immunity, so high in fact that a Melbourne hospital is doing a study on a COVID ward, using intravenous zinc. It appears that zinc has been found to be very low in the very ill. Zinc is anti-microbial, and it helps absorb Vitamin D. Zinc is also important in activating an enzyme that removes toxins. Quercetin is a bioflavonoid and zinc ionophore, which means it helps carry zinc into the cell thereby enhancing the bodies availability to use zinc (bioavailability).

Vitamin D

80% of how you absorb Vitamin D is due to genetics and deficiency is particularly common. Vitamin D inhibits inflammation, fights infection and is an immunomodulator hormone and according to this study, Vitamin D can prevent COVID-19infection-induced multiple organ damage due to its ability to increase ACE2 and decrease ANG 2.

Medicinal Mushrooms

From fighting cancer to managing stress, medicinal mushrooms are making headlines. Due to “Fantastic Fungi” on Netflix, many companies stocking these heavily dosed healing compounds have sold out. Supporting immunity, brain health, stress and the cardiovascular system as well as athletic performance and stamina, what is not to love. For a great summary on all the benefit, search here.

Capsulated or powder forms can be found. A dash of powder in the morning coffee can work well. Examples of medicinal mushrooms are Turkey Tail, Shitake, Cordyceps, Reishi and Lions Mane.

Glutathione

Glutathione is the main antioxidant for the brain, it cleans up toxins, helps produce, protect and repair DNA and high amounts are found in the liver. It recycles vitamins A and C and amplifies other supportive nutrients. This study supports that low glutathione levels were found in the sick. It is the principal nutrient that helps the liver deal with chemicals, including drugs. Foods containing glutathione are anything sulphur containing such as garlic, avocado, broccoli, cauliflower, cabbage, brussels sprouts, beetroot, parsley, grapefruit and spinach. This research paper concluded that a decrease in glutathione is a risk factor for chronic diseases.

Vitamin A

Vitamin A is essential in protecting epithelium and mucous membrane integrity in the body, highly important in the respiratory system. It has a critical role in enhancing immune function. Cellular differentiation, maturity and immunity all require Vitamin A. It’s great for the skin and eye health, reproduction and fertility, healthy bones and wound healing. Deficiency can be present with long term fat malabsorption, gut problems, gall bladder and pancreatic issues and autoimmune conditions.

It would remiss not to include Vitamin E here. Vitamin E relies on glutathione, selenium and active B3 to be recycled. It is a strong antioxidant and is important for tissue repair, helping stabilize cell membranes. It also supports the role of Vitamin D in the body, improves blood flow and reduces cholesterol.

COQ10 is highly heart protective, the active form being called Ubiquinol, used best in conjunction with selenium. It also regenerates other antioxidants, stimulates cell growth and inhibits cell death.

A few herbs deserve a mention including pomegranate, clove and barberry ( available form Persian supermarkets). A lot of herbs have antimicrobial and anti-parasitic benefits and their introduction into the diet can be highly beneficial.

A good balanced diet is therefore the key to support immunity including eating more vegetables of course. No new news there. Limit alcohol intake and of course exercise, as exercise has a significant impact on the health of the cardiovascular system. Reducing stress wherever you can is so important and difficult in these times, so please seek help if required. Long term stress suppresses innate and adaptive immune responses. Contact your health care provider for more information or seek help if you have symptoms as the faster you receive care, the better the outcomes. The more you can reduce inflammation in your body, the stronger it will be.

 

Senior man is suffering from pain in lower back

Spinal Complaints In The Older Generation

Are you over 65? If yes, then you make up 1 in 7 of the population and you contribute to 9% of the total disability for musculoskeletal conditions! – Disease and disability increases with age and research into this area are significantly important due to the debilitation that it can present.

Study – Spinal Pain in older women and associated Comorbidities

A study involving 579 older community dwelling women with spinal pain found that they had significantly lower mental and physical quality of life scores as well as associated obesity (or were found to be overweight), increased evidence of diabetes, pulmonary comorbidity and cardiovascular comorbidity. Comorbidities were significantly more common in women with spinal pain that in women without spinal pain. It also found that an increase in comorbidities increased the chance of experiencing spinal pain.

Study – Rehabilitation or Spinal Manipulation – Does is Help Older Adults’ with Back Pain?

This study involved 230 individuals over 65 with subacute lower back pain. They had supervised rehabilitation or spinal manipulative therapy (SMT) treatment over a 12 week period with self reported outcome measures of pain severity, back disability, health status, medication use, satisfaction and care and global improvement at weeks 4, 12, 26 and 1 year. The 3 groups were: home exercise: home exercise and SMT: SMT, home exercise and supervised rehabilitation. Pain severity was reduced by 30-40% with the largest difference favouring SMT and home exercise over home exercise alone. The two groups were significantly superior to home exercise alone with satisfaction of care.

Study – Short term and Long term Treatment Chiropractic for neck and low back pain – which is better?

This study involved two groups of 12 weeks of care versus 36 weeks of care for back and neck related disability in older adults.

Both the short term and long term groups reported significant improvements in back disability and the long term management group experienced self -reported greater improvement in neck pain, functional ability and balance at week 36. These findings may be important for healthy aging and spinal care in the elderly and warrant further investigation.

Other Studies

A Nordic Study – Maintenance Spinal Care as Key to Prevention of Low Back Pain

“It has been found that for individuals with recurrent or persistent non-specific low back pain (LBP), exercise and exercise combined with education have been shown to be effective in preventing new episodes or in reducing the impact of the condition. Chiropractors have traditionally used Maintenance Care (MC), as secondary (aiming to reduce the impact of a condition (LBP) that has already manifested) and tertiary prevention strategies (aiming to reduce the impact of persistent or chronic LBP). This is usually done by helping people manage long-term, often complex pain conditions in order to improve their quality of life and ability to function. The aim of this trial was to investigate the effectiveness of MC on pain trajectories for patients with recurrent or persistent LBP”.

Maintenance care is similar to servicing a car or visiting a dentist for teeth cleaning, even though you brush your teeth regularly. The main hypothesis for spinal maintenance care is that treatment may improve biomechanical and neuromuscular function thereby reducing the risk of relapse into pain. This study was actually done on 328 people between the ages of 16-65 years.

The definition of maintenance care is “…a regimen designed to provide for the patient’s continued well-being or for maintaining the optimum state of health while minimizing recurrences of the clinical statue” and “…treatment, either scheduled or elective, which occurred after optimum recorded benefit was reached, provided there was not evidence or relapse”

Hyperkyphotic posture (Dowagers Hump posture) predicts Mortality in Older Community-Dwelling Men and Women

An increase in the thoracic (mid back curve of the spine) has associated risk factors of vertebral fractures, degenerative disc disease, muscle weakness, decreased mobility and according to this study of 1353 individuals, an increase in mortality. Hyperkyphosis was specifically associated with an increased rate of death due to atherosclerosis concluding that men and women with hyperkyphotic posture have higher mortality rates.

Some case reports suggest that myofascial, spinal, and scapular mobilization techniques improve postural alignment in patients with hyperkyphosis. Physical therapists reported reduced hyphosis after soft tissue myofascial, neurodevelopmental, spinal, and scapular mobilization, and active therapeutic movement techniques.

Why not consider a Chiropractor

Our Sydney chiropractors have a special interest in posture correction and are here to help. Our care is gentle and effective care is possible for many. Exercise alone is often not enough for pain reduction, improving function and movement patterns. Even for old or chronic injuries, improvement in functionality and pain scales can still be possible, We have found that our gentle care, with exercise prescription and combined with the application of low-level laser therapy can really make a difference.

 

 

Rotator Cuff Injuries

Why Does My Shoulder Hurt? Rotator Cuff Injuries Explained

A pain in the shoulder region is a common musculoskeletal condition. When it is of no specific cause, it is often given the general diagnostic term of rotator cuff related shoulder pain (RCRSP). Simply, it is an umbrella term that can encompass a spectrum of shoulder conditions including tendinopathies, impingement syndromes and rotator cuff muscles tears.

RCRSP are the most common forms of should pain, often presenting with pain and weakness, particularly on shoulder elevation and external rotation (turning the hand to an outwards direction).

Most often, pain is precipitated by an event that has involved an excess or incorrect load. Many factors can also contribute including genetics, co-morbidities, lifestyle factors, central nervous system disturbances, psychosocial and even biochemical factors.

The difficulty with assessing the shoulder lies in the fact that the tendons of the rotator cuff sling create an intimate relationship with the surrounding capsule, ligament and bursal tissue. Due to this fact, the possibility of individually assessing each muscle/tendon complex in isolation through orthopaedic testing is not 100% accurate. A comprehensive clinical interview and examination is still however very important in providing a working hypothesis.

Rotator cuff injury Treatment & Exercise

How Do I Get Better – the evidence

There is strong evidence for the benefits of multiple forms of exercise as the most important management strategy. Included are such things as shoulder blade stability, strengthening of the rotator cuff muscles and shoulder flexibility. There is moderate to high level of evidence for the combination of manual therapy with exercise.

There appears to be limited benefits in corticosteroid injections for rotator cuff injuries, potentially only for short term benefits for some and the evidence for medium or long term use is unclear.

PRP or Platelet-rich plasma is also another form of injectable therapy however researchers concluded it had negligible to only a small degree of success. These findings are not surprising as it is well documented that pain is often poorly correlated with tissue pathology. A lot more research into surgical repair is required including methodology improvements and placebo controls as at present there is not a great support for a non-conservative procedure.

Manual Therapy for rotator cuff injury – from our Sydney chiropractic clinic experience alone, we have found that many shoulder injuries come from the sustained loading of the shoulder muscles due to poor postural control. Compression at the collar bond joint through rounded shoulders is common. The shoulder blades essentially drift outwards away from the thoracic spine causing the muscles under the shoulder blade to overload as well as all the important sling muscles of the shoulder joint. Micro-tears can then become a common feature. Also, through poor postural control, restrictions in the thoracic spine are common. In some cases, the nerve supply to these important muscles can then become compromised and a lack of ‘firing’ is possible causing significant weakness. Manual therapy and specific muscle retraining exercises are then often required. Postural control exercises are therefore very important to implement regularly, Taping is a useful technique for support, relief as well as acting as a reminder.

Immerging Therapy For Rotator Cuff Injury

We have found that low level laser (LLLT) for healing is helpful. More research is required in this immerging field. The theory behind implementing low level laser is that it stimulates energy within the cell. When energy is increased, healing can fasten. One of the most commonly damaged muscles is called the supraspinatus. In many people, the blood supply to this muscle is very poor and it needs all the help it can get for recovery. With the use of the photohaemotherapy application (increasing the blood supply) in LLLT to this muscle this procedure could be potentially significant in the recovery.

In summary, for many people shoulder pain can come on suddenly from what can appear an insignificant event. Consider your posture and consider a Chiropractor for shoulder pain to improve neuromuscular control.

patellofemoral pain syndrome runners knee

Running & Patellofemoral Pain Syndrome

Patellofemoral Pain Syndrome (PFP), pain at or near the knee cap, is traditionally known as movie-goers knee or patella tracking disorder. It actually accounts for almost 50% of all running injuries and is usually a poorly localised pain found around, near or under the knee cap. It has a greater predilection in females and is often aggravated by running hills, descending stairs, lunging, squatting or sitting for prolonged periods. Read more

knee osteoarthritis treatment sydney

Managing Knee Osteoarthritis

Knee Osteoarthritis (KOA) is both a prevalent and challenging condition to treat, commonly been seen as a structural problem with only surgery as the solution.

A recently published PubMed article is titled “Arthroscopic surgery for knee osteoarthritis? Just say No” -offering these suggestions below as an alternative.

Using analgesia – However, it does discuss gastric toxicity.

Nonpharmacological therapy – stating “physical therapy and regular exercise typically reduce pain and improve function of an arthritic knee. Acupuncture may have a small benefit as well.”

Consider a combination of glucosamine and chondroitin – The two combined may provide some relief associated with moderate to severe knee osteoarthritis.

If you are interested in this article, please visit and you can follow the reference points.

One suggestion this article fails to mention is Low Level Laser Therapy (LLLT) or Photobiomodulation for pain relief. Published articles of the benefits of LLLT have been available for at least the last 8 years, around the length of time we first received our Low Level Laser unit to our Lane Cove Chiropractic Centre.

Alignment is the Key

As Chiropractors, we understand this paragraph perfectly and couldn’t have said it better so..

“The human body is a complex mechanical unit composed of many joints held together by muscles, tendons and cartilages which also allow articulation. Gravitational forces must be balanced at all times at each link.

The line of gravity, one of the body’s most important factors as described by Harada, passes through the outer ear-opening and intersects the center of gravity of the human body (located adjacent to the sacrum) and the center of the knee joint.

The understanding of the function of the locomotive apparatus in the upright position and the dynamics of the body is one of the most important factors, so that the gravitational torque has a tendency to extend the knee joints in our daily life”

Here is the article in full for you with the conclusion that low level laser therapy can provide pain relief. One study in 2014 on rat knees showed prevention of degradation of cartilage with LLLT. More studies of course need to be done, but this is promising information. This particular article states “LLLT stimulated cellular activity of cartilage repair and collagen synthesis, accelerating the breakdown of cartilage destroyed by collagenase and stimulating the fibroblast to synthesize repairing collagen III”

In summary, it is saying growth and repair of cartilage! Further information on Low Level Laser Therapy is found below.

For non-traumatic causes of knee pain, we especially like to look for the cause and not purely treat just the symptoms. Non-traumatic knee pain simply means that pain that has not been caused from a direct trauma to the knee itself. Many football playing injuries or skiing injuries for example can have a direct trauma cause of KOA. The majority of knee osteoarthritis cases we have seen however have been the non-traumatic type and respond to a thorough investigation as well as addressing potential foot function issues, hip and pelvic alignment and muscle weakness (particularly the gluteal muscles). Remember, the foot bone is connected to the thigh bone, which is connected to the hip bone! The knee is the middle joint and is thereby subjected to altered functionality if the foot and the pelvis have any distorted movement patterns as mentioned in the above PubMed paragraph. Our in house Foot Leveller orthotics are actually called “Pelvic Stabilisers” for good reason!

Further Knee Osteoarthritis Treatments

Hyaluronic acid appears superior to corticosteroid injections with beneficial effects on pain and function. Published results cause consideration of this with the low-quality evidence supporting corticosteroid injections.

Platelet-Rich-Plasma (PRP) currently appears to be beneficial and superior to placebo and Hyaluronic Acid both in function and pain.

Glucosamine and Chondroitin maybe beneficial and appears more efficacious that paracetamol.

Exercise has high quality evidence supporting this treatment for decreasing pain, improving functionality and the quality of life. Certainly, it is important to have the correct Knee Osteoarthritis exercises given particularly with examination of all associated muscle systems including those associated with hip stabilisation.

Knee Replacement. Let’s face it, sometimes things are beyond repair, however conservative treatment would always be the first recommendation to try.

On a final note, Look to the cause to help create the solution. And remember, when one part of the body is not functioning well, it cannot be isolated. In time, it will cause distortions elsewhere. Good mechanical functioning creates far better loading patterns.

For further reading of the benefits of Low Level Laser Therapy, please click Here and contact us directly if you require the research papers addressing the above mentioned treatments.

If you need a chiropractor for knee pain treatment in Sydney, please get in touch today.

Research Hub- Latest News in Science